北京大學生物醫學前沿創新中心

聯系方式

E-mail：hesheng@www.jhlqc.com
辦公電話：（010）80726688-8751
辦公地點：昌平區中關村生命科學園28號

研究組主頁：

劉河生

BIOPIC客座教授

個人履歷

2021-現在北京大學，北京大學生物醫學前沿創新中心(BIOPIC)，教授

2021-現在昌平實驗室，腦科學與類腦研究部，首席科學家

2019-2021 美國南卡羅萊納醫科大學，神經科學系，Smart State講席教授

2019-2021 美國南卡羅萊納醫科大學，神經影像計算中心，主任

2012-2019 美國哈佛大學附屬麻省總醫院，腦個體差異實驗室，主任

2016-2019 美國哈佛大學醫學院，放射學系，副教授

2012-2016 美國哈佛大學醫學院，放射學系，助理教授

2009-2012 美國哈佛大學醫學院，放射學系，講師

2006-2009 美國哈佛大學附屬麻省總醫院，放射學系，博士后

2004-2006 美國華盛頓州立大學，計算機科學，博士后

2003，清華大學，工學博士

1997，清華大學，工學學士

主要研究方向

劉河生教授實驗室長期從事腦功能成像研究，致力于將腦功能成像技術推向重大腦疾病的臨床應用。研究方向包括(1)個體上的大腦功能區的精準剖分。發展可靠、精準的個體化腦功能區剖分技術，研究大腦的社會認知、情感、記憶、語言等基礎認知功能；(2)重大腦疾病的臨床轉化研究?；趥€體化腦成像分析技術識別神經精神以及兒童發育，如情緒障礙、孤獨癥、卒中、帕金森等腦疾病的生物學標記物，優化患者的治療和康復；(3)重大腦疾病的臨床干預的設備研發。

獲獎及榮譽

2021年科技部創新人才

2021年美國國際創傷后應激障礙學會Pierre Janet最佳論文獎

2019年美國南卡羅來納州 Smart State Endowed Chair

2013年腦與行為研究基金會（NARSAD）青年研究員獎

代表性論文及論著

劉河生教授為第一作者或通訊作者

Google 學術：https://scholar.google.com/citations?hl=zh-CN&user=86URon8AAAAJ

1.Peng X, Liu Q, Hubbard C, Wang D, Zhu W, Fox MD, Liu H., Robust dynamic brain coactivation states estimated in individuals, Science Advances, 2022

2.Trambaiolli, L. R., Peng, X., Lehman, J. F., Linn, G., Russ, B. E., Schroeder, C. E., Liu, H. #, Haber, S. N. #, “Anatomical and functional connectivity support the existence of a salience network node within the caudal ventrolateral prefrontal cortex”, Elife, 11, 2022.

3.Cui W, Wang Y, Ren J, Hubbard CS, Fu X, Fang S, Wang D, Zhang H, Li Y, Li L, Jiang T., Liu H. “Personalized fMRI delineates functional regions preserved within brain tumors”. Annals of neurology, 2021.

4.Wang D., Peng X., Pelletier-Baldelli A., Orlov N., Farabaugh A., Nasr S., Eryilmaz H., Fava M., Holmes A., Roffman J.L., Liu H. #, Holt D. #, “Altered temporal, but intact spatial, features of transient network dynamics in psychosis”, Molecular Psychiatry, 2021

5.Yan Y., Dahmani L., Ren J., Shen L., Peng X., Wang R., He C., Jiang C., Gong C., Tian Y., Zhang J., Guo Y., Lin Y., Li S., Wang M., Li L., Hong B., Liu H., "Reconstructing lost BOLD signal in individual participants using deep machine learning", Nature Communications, 2020

6.Stoecklein S., Hilgendorff A., Li M., F?rster K., Flemmer A.W., Galiè F., Wunderlich S., Wang D., Stein S., Ehrhardt H., Dietrich O., Zou Q., Zhou S., Ertl-Wagner B., Liu H. “Variable Functional Connectivity Architecture of the Preterm Human Brain: Impact of Developmental Cortical Expansion and Maturation” Proc Natl Acad Sci USA, 2020

7.Lebois L., Li M., Baker J.T., Wolff J., Wang D., Grinspoon E., Winternitz S., Ren J., Ressler K., Liu H. #, Kaufman M. #, “Large-scale functional brain network architecture changes associated with trauma-related dissociation”, Am. J. Psychiatry, 2020

8.Shen L., Jiang C., Hubbard C.S., Ren J., He C., Wang D., Dahmani L., Guo Y., Liu Y., Xu S., Meng F., Zhang J., Liu H.# , Li L. # “Subthalamic nucleus deep brain stimulation modulates two distinct neurocircuits”, Annals of Neurology, 2020

9.Stoecklein, V.M., Stoecklein, S., Galiè, F., Ren, J., Schmutzer, M., Unterrainer, M., Albert, N.L., Kreth, F.W., Thon, N., Liebig, T. and Ertl-Wagner, B., Tonn J.C., Liu H. “Resting-state fMRI Detects Alterations in Whole Brain Connectivity Related to Tumor Biology in Glioma Patients.” Neuro-Oncology. 2020

10.Liu H., Xiaolong Peng X., Dahmani L., Wang H. , Zhang M., Shan Y., Rong D., Guo Y., Li J., Li N., Wang L., Lin Y., Pan R. Lu J., Wang D., “Different stroke-induced striatal lesions lead to differential structural brain reorganization” Neurology, 2020

11.Wang D., Li M., Wang M., Schoppe F., Ren J., Chen H., Ongur D., Baker J.T., Liu H., “Individual-specific functional connectivity markers track dimensional and categorical features of psychotic illness”, Molecular Psychiatry, 2020

12.Li M., Wang D., Ren J., Langs G., Stoecklein S., Brennan B.P., Lu J., Chen H., Liu H., “Performing group-level functional image analyses based on homologous functional regions mapped in individuals”, PLoS Biology, 2019

13.Tang W.#, Liu H.#, Douw L., Kramer M.A., Eden U.T., H?m?l?inen M.S., Stufflebeam S.M., Dynamic connectivity modulates local activity in the core regions of the default-mode”, Proc Natl Acad Sci USA，2017

14.Wang D, Buckner RL, Fox MD, Holt DJ, Holmes AJ, Mueller S, Langs G, Pan R, Qian T, Li K, Baker J, Stufflebeam SM, Wang K, Wang X, Hong B, Liu H. “Parcellating Cortical Functional Networks in Individuals”. Nature Neuroscience, 2015

15.Mueller S., Wang D., Pan R., Holt D., Liu H., “Abnormalities in hemispheric specialization of caudate nucleus connectivity in schizophrenia”, JAMA Psychiatry, 2015

16.Zeng L., Wang D., Fox M.D., Sabuncu M., Hu D., Ge M., Buckner R.L., Liu H., “Neurobiological basis of head motion in brain imaging”. Proc Natl Acad Sci USA, 2014

17.Mueller S., Wang D., Fox M.D., Yeo B.T.T., Sepulcre J., Sabuncu M.R., Shafee R., Lu J., Liu H., “Individual variability in functional connectivity architecture of the human brain”, Neuron, 2013

18.Liu H., Stufflebeam S.M., Sepulcre J., Hedden T., Buckner R.L., “Evidence from Intrinsic Activity that Asymmetry of the Human Brain is Controlled by Multiple Factors”, Proc Natl Acad Sci USA, 2009.

19.Liu. H., Agam Y., Madsen J.R., Kreiman G., “Timing, timing, timing: fast decoding of object information from intracranial field potentials in human visual cortex”, Neuron, 2009.